Observing the creation of novelties within a certain period of time, their interwovenness appears as a web of novelties.
This perspective is clearly different from that postulating that chaperones are capacitors of evolution because they typically mask phenotypic expression of mutations and thus maintain a reservoir of variation needed for the creation of novelties [ 12, 28, 37, 66, 88].
The preferential integration of Lep1 Helitrons in proximity to gene-coding regions results in the creation of genetic novelty that is shown to impact gene structure and function through the introduction of novel exon sequence (exon shuffling).
Because it provides the raw material for gene diversification and hence the creation of genetic novelty, gene duplication is recognized as a major force in the evolution and adaptation of species [ 1, 2].
The mutator genotype may confer a temporary selective advantage for the bacteria under stressful conditions, as it allows for the creation of genetic novelties, including stochastic mutations and incorporation of a great diversity of exogenous DNAs [ 12, 13].
Notable are the ideas of Joseph Schumpeter, who argues that innovation consists of novelty, that is, the creation of completely new products and services (Schumpeter 1961).
