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Conical shape is chosen to reduce the surface contact area, while 45° tilt creates the adhesion asymmetry necessary for walking (SEM image in Figure 2d,e).
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As cells move forward they make use of integrins to create the adhesions that allow migration to proceed.
Each hair of the gecko's foot produces just a miniscule force through van der Waals' interactions, but millions of hairs collectively create the formidable adhesion [47].
This is supported by the observation of the appearance of small focal adhesions simultaneously with the disappearance of membrane blebs during the spreading of cells that suggests a role in attachment by creating the focal adhesions in the basal membrane.
Taken together, our results demonstrate that sequential coordination of apoptosis and epithelial architecture with selective adhesion creates the zigzag hair alignment.
The basic chip design consisted of 91 gelatin spots (300 μm in diameter) in a hexagonal arrangement on a glass substrate that served as the cell adhesion area; the region without gelatin spots was modified with polyethylene glycol to create the non-adhesion area.
This range of distances, up to 15 nm, is considered to be the limit for the adhesion event that creates the fusion between the vesicle and the presynaptic membrane that can lead to exocytosis [ 24].
Direct current (DC) cathodic plasma processes including plasma treatment and plasma deposition were used to create the water-insensitive adhesion of organic coatings to aluminum alloys.
One of the possibilities is that intensive actin polymerization in the lamellipodium creates conditions where the adhesion formation is favored.
Plausibly, the flow rate of a compressible network will locally decrease in front of focal adhesions, creating the differential network kinematics.
Atomic/molecular understanding of adhesion should be extremely beneficial in selecting or creating the appropriate materials to attain the desired adhesion strength.
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