"creates significant problems" is correct and usable in written English.
You can use it to refer to a situation or thing that causes difficult or serious issues. For example, "Global warming creates significant problems for the environment."
Different communication requirements necessitate different network solutions, and these different network protocols can create significant problems of compatibility when networks are interconnected with one another.
Di Natale explained the shift by his party from 13%to15%5% over the course of Thursday as a desire to fix an issue that was creating significant problems for farming and horticultural communities.
"They are usually based on border control and law enforcement, yet we know that detention for a child is the worst thing that can happen and can create significant problems [for] a child's development.
How will the blue-collar voters in these states respond when Senators up for re-election in 2018 like Debbie Stabenow are forced to make their opposition to this a key plank of their campaigns?" Statements like these could create significant problems for the Administration's lawyers tasked with defending the lawsuits to come.
The ACT's opposition leader, Jeremy Hanson, said during Tuesday's debate that the uncertainty surrounding the new same-sex marriage regime created significant problems for couples, and he suggested the territory could be liable to compensation if it pushed ahead of the tolerance of the commonwealth, rather than waiting for the legalities to be settled.
These handovers create significant problems if there is no minimum number of femtocells in the neighbor femtocell list.
Bora mean velocity rarely exceeds 20 m/s, while its strong gusts create significant problems for engineering structures, traffic and agriculture.
Unfortunately, this p2p surge has created significant problems to network operators by generating large volumes of inter-AS traffic.
