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The gene defect creates fragile skin that easily tears, resulting in painful blisters and sores.
The description of errors in replication initiation of a common fragile site but not in its replication progression (76), shows that sequence repetition not necessarily creates fragile DNA.
Second, the presence of neighboring nicking sites on opposite strands creates "fragile sites" leading to double-stranded breaks during the nick-labeling process that cannot be bridged by any DNA molecules.
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Heidi Bucher, Hannah Wilke and Hesse all used latex to create fragile impressions.
The parents are very intelligent, devoted and loving, but they were ruled by their fears and they created fragile children".
Mr. Wyatt uses his drumming to create fragile, midtempo grooves; they are the platform for extraordinarily moving melodies.
In the figures of Rufus Scott (Another Country) and Leo Proudhammer (Tell Me How Long the Train's Been Gone) Baldwin created fragile characters shouldering the weight of what he saw as a cruel and oppressive world.
He gives us a handful of touching boyhood memories — building model airplanes with Dad, creating delicate dragonfly-fragile machines that actually flew out of wood and paper and plastic film — but he never really grapples with the shadow that this towering figure cast over his life, or his reasons for rebelling so thoroughly against his father's ideals and ambitions.
We then determined the size of each region and classified the regions as having or not a fragile site by creating a fragile dummy variable (if a region has at least one fragile site the dummy will take the value 1, and if the region does not contain any fragile site the dummy takes the value 0).
Veronique Branquinho created a fragile drape from woven ribons across sweaters and dresses.
It is inequality that has helped create our fragile banking system.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com