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Longer travel time to the dialysis unit creates a substantial burden for many patients.
This creates a substantial risk for secondary brain injury in those with recalcitrant intracranial hypertension.
The transformations of ENMs are subsequently facing a major ecological transition that is expected to create a substantial toxicological effect towards the ecosystem.
The policies the administration pursued in the first term have already had a substantial effect, playing a role in creating the recent wind and solar boom.
The candidates' ads have had a substantial effect.
Meyersson: Industrial espionage had quite a substantial effect in East Germany.
"To have a substantial effect, people would have to anticipate substantial purchases," Mr. Kohn said.
"Changing the name would have a substantial effect on our business".
"The fear contagion," Professor Siegel said, "could have a substantial effect on the markets".
Economists said increased government spending could have a substantial effect on the economy.
Or, perhaps neither is having a substantial effect.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com