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This psychedelic substance then crosses the blood-brain barrier and binds to a specific serotonin receptor known as 5-HT2A, creating a profound alteration of consciousness that has been described as a mystical event, a spiritual journey or simply a "trip".
This psychedelic substance then crosses the blood-brain barrier and binds to a specific serotonin receptor known as 5-HT2A, creating a profound alteration of consciousness that has been described as a mystical event, a spiritual journey or simply a "trip". Psychedelic compounds in LSD, ayahuasca and mescaline bind to this same receptor.
His passing creates a profound void in all our hearts.
This back and forth creates a profound uneasiness that is hard to shake.
It's going to take a variety of approaches to create a profound systemic change.
This rate of change signifies a profound alteration of global climate, and in turn will radically alter agriculture, human occupation patterns and the distribution of the Earth's natural ecosystems.
This state of development required a profound alteration in the genetic template to produce short pelvic blades, a forward-pointing big toe (adducted hallux), and other bipedal traits.
But it's also about a profound alteration that these scientists wrought in the way we look at reality.
But only one book had such a decisive impact that I can date to it a profound alteration in my worldview and even behaviour.
Paget Disease of the bone is a metabolic disorder which leads to a profound alteration of the bone's architecture.
Overall, cannabis may provoke a profound alteration in brain neurotransmission and, in particular, in the mesolimbic system, where it can rearrange the molecular architecture at the synaptic level.
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CEO of Professional Science Editing for Scientists @ prosciediting.com