An example of a translocation capable of creating a differentiation block is the recurring t(3 12)(q26;p13) translocation.
A protocol with the specified aim of creating a differentiation process capable of creating dopaminergic neurons for transplantation in T-flasks has been developed [ 89].
Translocation events, duplications, inversions, or deletions would be favored by BRCA pathway defects and they represent potential ways to create a differentiation block typical of AML.
It felt that its proprietary software and content created a product differentiation, although that required translating its service into seven languages.
The introduction of the PUFA index in this study examining possible associations between dental decay and low BMI appeared to be relevant, since it created a clear differentiation in the findings.
"We believe that this would help the government by creating a clear differentiation between temporary and permanent migration, help universities whose international character is essential to their future success, and help the UK by contributing to economic growth".
By snagging the UK rights for CSI in 2001, it created a valuable point of differentiation from its terrestrial rivals: here was a channel prepared to put hot US TV programmes in primetime, at a time when the BBC and ITV were more interested in nurturing homegrown talent.
To elucidate the role of MVI in myoblasts (and possibly in their differentiation), we created a C2C12 cell line with stable expression of a MVI shRNA construct.
Since the Sox2 KO is lethal in early embryonic development (10), to precisely define the role of Sox2 in osteoblast proliferation and differentiation we created a conditional knock-out (CKO) of the Sox2 gene in the osteoblastic lineage utilizing mice with a Sox2flox/geo genotype (hereafter referred to as Sox2flox/-).
Hence, two opposite evolutionary hypotheses can let us expect either that isolation mechanisms have resulted in the subdivision of A. cajennense into genetically distinct populations, or that persistent gene flow, maintained by dispersal on hosts, has created a genetic gradient of progressive differentiation throughout the tick distribution range.
