Sentence examples for create significant challenges from inspiring English sources

This will create significant challenges for many micro businesses and sole traders, some experts warn.

In addition, the extremely high temperature and pressure conditions associated with WDM create significant challenges for detailed experimental studies5.

But if those plans are adopted, space reserved for a memorial below ground level could create significant challenges for officials in planning the underground elements of a rebuilt trade center site.

The operation of the photo-emission source and the control of the subsequent pulse of electrons (containing as many as 5×107 electrons) create significant challenges for a standard microscope column that is designed to operate with a single electron in the column at any one time.

However, the structural complexity of most temperate watersheds (i.e. connections among shallow soils, deep aquifers, the atmosphere and streams) and the dynamic seasonal changes that occur within them (i.e., plant senescence which impacts evapotranspiration) create significant challenges to characterizing or quantifying hydrologic connectivity.

"Geopolitical issues create significant challenges, but executives are determined to overcome perceived barriers and secure – or expand – their presence in markets that support their long-term strategic goals," Steve Krouskos, a global vice chair at EY, said.

Modern electronic commerce creates significant challenges for decision-makers.

This creates significant challenges to identifying targeted therapies that are effective against multiple AML subtypes.

The advance in NGS technologies has also created significant challenges in bioinformatics.

This creates significant challenges in both training and measuring surgical proficiency.

E-commerce has created significant challenges for the administration of sales taxes, especially when transactions cross national boundaries.