Sentence examples for create mutations from inspiring English sources

To create mutations in a gene of interest, including point mutations, short insertions, or deletions.

Particular error-prone DNA polymerases appear to create mutations in hotspots on the top and bottom DNA strands throughout the target and the SHM process.

Nuesslein-Volhard and her collaborators at other institutions will create mutations in zebrafish by treating eggs with mutagenic chemicals, then scan the resulting embryos and larvae--whose number is expected to reach 17 million--for physical aberrations.

And several groups plan to inject CRISPR into a developing mouse; the goal is to create mutations that act as barcodes and allow scientists to track cell lineages as they differentiate.

Intragenic excision and re-integration has previously been reported in mouse T2/Onc tumors [10], [11], [17], [18] and was interpreted to represent the selection of integrations that create mutations favorable for tumor cell survival and maintenance.

ssDNA oligonucleotides have been used to create mutations by gene targeting in yeast using Rad51, Rad52, and Rad59 annealing activities [99], [100] and in E. coli using the phage λ Red beta protein [97], thus demonstrating the plausibility of this model.

In brief, the populations were simulated for 1000 generations at an effective size of 100 in order to create mutation drift balance and LD between the markers and the genes.

For nearly a century, scientists have been creating mutations in fruit flies and looking for such an effect, said Dr. Michael Rose, an evolutionary biologist and fruit fly researcher at the University of California at Irvine.

These genes, which encode three novel proteins called steerins, were first identified in C. elegans by creating mutations that caused certain types of cells to wander all over the worm during development, rather than going to their correct destinations.

But he previously described the work at a public meeting, and various publications have reported that the experiment involved creating mutations in the virus and then squirting it into the respiratory tracts of ferrets.

When the going gets tough for agricultural plants, for instance, the number of transposable elements seems to decline.In humans, some retroviruses may behave in similar ways, causing diseases by jumping around and creating mutations.