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That has made it far easier to create altered animals.
Synthetic oligonucleotides were ligated to create altered CtrA binding sites and corresponding promoters with varied transcription strength.
Successes involving one or a few genes, as well as global genomic approaches are reviewed with an eye to future developments that would engage novel genomic and systems-biology tools to create altered or semi-synthetic strains with superior tolerance characteristics for bioprocessing.
Cognate peptides may be modified at key T-cell receptor (TCR) recognition residues to create altered peptide ligands (APL).
For example, RPs, rRNAs and various accessory factors involved in pre-rRNA processing are modified post-transcriptionally and, hypothetically, variations of these processes could also create altered ribosomes.
The expansion/contraction of SSR repeats and non-synonymous substitutions of SNP loci in the functional domain of genes encoding variable amino acid residues might create altered secondary structure of proteins and functional domain regions that possibly affects the DNA binding and transcriptional activity of target gene during seed development.
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In virtual worlds like Nicktropolis, visitors create alter egos — termed avatars — which then interact with other avatars and the Web site environment, like people do in the physical world.
Urbanisation creates altered environments characterised by increased human habitation, impermeable surfaces, artificial structures, landscape fragmentation, habitat loss, resulting in different resource loss pathways.
Often tinged with a distinct sense of hippie burnout culture and laid-back SoCal zeitgeist, Landau's images capture an impermanent LA through scenes that have been visibly created, altered, and/or destroyed by its transitory population.
Each oligonucleotide is created to match the selected region of the target gene (perfect match, PM), while a similar oligonucleotide is created altered in the 13th position to control for non-specific binding (mismatch, MM).
Each oligonucleotide is created to match the selected region of the target gene (perfect match, PM), and a similar oligonucleotide is created altered in the 13th position to control for nonspecific binding (mismatch, MM).
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