However, whilst specific residues within the CTD create a docking site for γ-tubulin, the entire region is required for the interaction, presumably by contributing to the conformation of the protein.
Therefore, the phosphorylation of PTPN18 on its DQSPAGS motif may create a docking site for ubiquitin E3 ligases, β-Trcp.
The activated JAKs phosphorylate the tyrosine residues on gp130 to create a docking site for Stat3 recruitment and in turn, activate Stat3 by phosphorylating its tyrosine 705 residue (Boeuf et al., 1997; Darnell, 1997).
Waterfront works are the specialty of George Trakas, a veteran land art practitioner who also created a dock on the Hudson for Dia:Beacon.
This is a nice feature that effectively creates a dock that hides when you're not using it, where apps that you have open can sit for easy swapping.
Phosphorylation of serine 573 (amino acid numbering refers to human RSK1 throughout) by ERK1/2 results in autophosphorylation at serine 380, which creates a docking site for another kinase, PDK1.
It has been previously shown that p210 BCR/autophosphorylateslates on Tyr-177, creating a docking site for GRB2.
At the onset of mitosis, Nlp is phosphorylated at Ser185 by Cdc2, creating a docking site for PBD of Plk1.
It decreases the binding of Fe65 29, 30 and creates a docking site for the peptidyl-prolyl cis/trans isomerase, Pin1 30.
Phosphorylation of Tyr682 in this domain creates a docking site for some cytosolic proteins containing a Src homology 2 domain, such as Shc, Grb2, and Grb7 12– 15.
