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However, association performance is not significantly affected by the coverage variance.
Finally, the proposed association method is evaluated with a realistic scenario and is analyzed to show the stability of the proposed method according to degree of the discrepancy between approximated and actual identification sensor coverage, variance of actual identification sensor coverage, and tracking performance.
Differences in coverage variance between the libraries were examined with the Ansari-Bradley test using MATLAB.
Using these thresholds, the boundaries of nuwts >100-bp were defined relative to the wBm genome using a sliding window approach to smooth coverage variance.
We found that libraries prepared from the two WGA time points were virtually indistinguishable in terms of mean coverage, variance in coverage, mean GC content, and number of putative chimeras (data not shown).
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In Section 4, the proposed method is evaluated with a realistic application scenario and is analyzed with nonideal problems such as the discrepancy between approximated and actual identification sensor coverage and variance of actual identification sensor coverage.
We did not observe either of these effects – both mean depth of coverage and variance were similar between single-copy and duplicate gene pairs – and we therefore conclude that capture efficiency in our study was not substantially impacted by the presence of paralagous genes.
Since the early 50s, when Roberta Cowell and Christine Jorgensen hit the headlines, media coverage of gender variance has focused on transsexual people, emphasising (if not sensationalising) the medical aspects of transition.
The cumulative coverage of data variance within the first 3 PCs is larger than 75%% in the case of the fingerprints MQN, SMIfp and APfp, which are relatively simple descriptions of the molecules resulting in a relatively low number of dimensions (Fig. 1a).
In general, both approaches have high power for detecting association, but the SEM approach performs better in terms of bias and coverage for the variance component,.
Eisenberg et al. reported high detection rates using high coverage, copy number variance (CNV) analysis and sequencing the 5′ UTR [ 27].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com