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This indicates, in general, an exceptionally low level of nonspecific adsorption given that at monolayer coverage the region shown in Figure 5 d would contain some 10 proteins.
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After finding excess coverage, we remove the reads to 'flatten' the coverage of the region with its surroundings.
We use the average coverage in the region of <25X (1/2 of the average HS1011 Illumina coverage) to focus on deletion regions likely to be unique in the HS1011 genome: average coverage >50X might indicate a paralogous region in HS1011 genome.
Collapsed or expanded repeats will present as the read coverage being greater or lower than the expected genome coverage in the region that has been misassembled.
The GS FLX shotgun sequencing produced ~30× coverage of the region and the BAC-end sequences provided an additional ~0.09× coverage.
Here, three of the platforms greatly reduce their coverage in the region of interest (Nimblegen being absent altogether), while Illumina exhibits good coverage.
We speculate that this represents extensive over-coverage and that similar results could be obtained using fewer reads and less coverage of the region.
We'll anchor it all around the Guardian's news coverage of the region.
Coverage from the region already suffers from a terrible imbalance on this score.
Coverage of the region's physical and human geography can be found in the article Africa.
That may be because, as of early March, the site's coverage in the region was still spotty.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com