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Incomplete coverage of statistical data.
We would like to point out that the major goal of our review is not a full coverage of statistical details but to provide sufficient information for the reader to acquire a basic understanding of major principles and assumptions that underly the methods.
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An extensive coverage of the statistical analysis can be viewed in the additional files (See additional files 6: full statistical analysis of CM10 S1, additional file 7: full statistical analysis of Q10 S1, additional file 8: full statistical analysis of CM10 S2 and additional file 9: full statistical analysis of Q10 S2).
The challenge in meeting the objectives of this textbook is to avoid being superficial in the coverage of a statistical test without getting overly detailed in its application.
As we may want to favor large coverage of chunks over statistical significance, the scope is broader.
We have compared the performance of our algorithm with that of existing algorithm using one artificial dataset in terms of affirmation score and one real-life dataset in terms of coverage, statistical difference from background and triclustering quality index score.
Variation in analysis mainly focuses on three aspects: (1) filtering of close and low coverage SNPs, (2) choice of statistical test and (3) choice between SNP specific counts or aggregate of allele specific counts across the haplotype.
Furthermore, we assessed the risk of overestimation, confidence interval coverage and statistical power of an indirect comparison involving two treatments, but we did not examine these statistical features for the direct comparison involving the same two treatments.
The lack of associated genes in I-CP may be a direct consequence of insufficient SNP coverage rather than a lack of statistical power.
But official figures almost certainly understate consumer spending in emerging Asia, because of the poor statistical coverage of spending on services.
Official figures show that China's consumer spending is currently only one-fifth of that in America (although that may be understated because of China's poor statistical coverage of services).
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CEO of Professional Science Editing for Scientists @ prosciediting.com