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Worldwide structural genomics projects are increasing structure coverage of sequence space but have not significantly expanded the protein structure space itself (i.e., number of unique structural folds) since 2007.
After preprocessing, between 15.1× (pool 2) and 22.2× (pool 4), coverage of sequence (paired-end and Titanium combined) was available for assembly.
By comparing coverage of sequence reads from sheared chromatin samples to those from sheared genomic DNA, we were able to separate technology-related sequencing biases from biologically meaningful effects.
The trCYK algorithm improves alignment accuracy and coverage of sequence fragments of structural RNAs in simulated metagenomic shotgun datasets.
Even though the coverage of sequence reads throughout the genome was not enough (only 0.02× coverage per line), their method provided useful results.
The Tallymer software was effective in a variety of applications to aid genome annotation in maize, despite limitations imposed by the relatively low coverage of sequence available.
Similar(37)
The average MS/MS peptide coverage of sequences that are supported by MS and EST data or exclusively by MS data alone is 14.3% and 5.25%, respectively.
In the KinG database, the coverage of sequences by Pfam domains, on a per-residue basis, ranges from 6 to 100%.
A high coverage of sequences from the clone libraries pooled for the two groupings was achieved (C = 93% and 95% for all colonies and six colonies respectively) and is further supported by rarefaction analyses (Figure 6).
Furthermore, the coverage of sequencing as a potential influence factor was not under consideration here.
Coverage of sequencing was at least 2-fold based on independent isolations.
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