Genes that are sensitive to eIF4E-mediated translation cover a range of cellular functions, including cell cycle control (cyclin D1), angiogenesis (VEGF), metabolism (ODC), and apoptosis (survivin and Mcl-1) among others (Rousseau et al, 1996; Graff et al, 2007; Mamane et al, 2007; Mills et al, 2008).
Cluster 2 consists of 41 genes that cover a range of different lysosomal functions, but subunits of the vacuolar H+ ATPase (Atp6ap2, Atp6v1a, Atp6v1b2, Atp6v1c1, Atp6v1d, Atp6v1g1, Atp6v1h) and components of the endo/lysosomal trafficking machinery (Lamp2, M6pr, Rab14, Rab7, Rab9, Snap23, Vamp7, Vps4b) are particularly prominent.
10, 25, 26 The 36 items cover a range of categories, including physical function (phyfu); physical role function (role limitations due to physical problems; phyro); bodily pain (pain); general health (genhe); vitality (vita); social function (sofu); emotional role function (role limitations due to emotional problems; emro); and psychological well-being (psyc).
The Tool is composed of a series of questions, which cover a range of general and influenza-specific laboratory functions such as, virology and biosafety, as well as the quality of those functions.
They cover a range of scenarios of how damage hampers functioning, and of how damage is passed on to the progeny upon division.
Objective functions can cover a range of cellular objectives [ 3], such as maximisation / minimisation of ATP consumption, but frequently (and particularly in the case of microorganisms) take the form of an assumed "biomass" function; a hypothetical reaction that mimics cell growth rate [ 4].
These ready-made (and classroom-tested) lessons and workshop sessions cover a range of fungal topics from cell structure and function, through biotechnology to health topics and plant growth and disease.
By using different doses of doxycycline to cover a range of Pho4-YFP expression levels, the gene-regulation function was assembled from single-cell measurements.
