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These cell responses also exhibited different temporal thresholds that were determined by time courses (data not shown) prior to experiments shown in Fig.  2.

Also, there was no significant difference in the DNA damage observed between the two courses, with no indication of cumulative damage or of changes in sensitivity to treatment in successive courses (data not shown).

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Plasma triglycerides essentially paralleled the retinol clearance curves over the same time course (data not shown).

Women receiving a full-course of IPTp-SP had slightly less knowledge of malaria and SP compared to women receiving a partial-course (data not shown).

The transient activation of many inflammation-related proteins has been observed during the early phase of the time-course (data not shown).

In all populations treated with UV-light, the percentage of necrotic cells (7AAD+ cells) was lower than 15% and did not increase during the time course (data not shown).

The hNGFR100E mutant induced a significantly lower activation of Erks, with respect to hNGF (Fig. 1E,H), which is not due to a different time course (data not shown).

To discount this, we have tested the IRF-3 protein levels by Western blotting and found no dramatic degradation of IRF-3 in our MDM during the HIV-1 infection course (data not shown).

No significant changes to tumour masses were observed after this short time-course (data not shown).

Ova-TR standard solutions in PBS with 1% BSA were completely stable over this time course (data not shown).

In these cells, the 5′ transcript was undetectable during the entire 96-h time course (data not shown).

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