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The free ADP time course was obtained by fluorescence stopped flow (Fig. 3).
Using seed ROI analysis, a seed reference time course was obtained by averaging the time series over the voxels in the bilateral ACCs.
The total ADP time course was obtained by the rapid quench flow method and it shows a transient burst of ADP formation, followed by a linear rise in ADP.
Partial radiological response was obtained in two patients (13.3%), stable course was obtained in nine patients (60%), and four patients (26.7%) showed progressive disease (died at 4 months after injection).
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Quantitative data encompassing both treatments and the entire time course were obtained for 62 metabolites.
Important safety information should, of course, be obtained, but the trial should be adequately powered to address the primary objective.
The marks secured by students in periodic formative assessments during the course and the summative assessment at the end of the course were obtained from departmental records.
Three classes of variables were used: A number of variables relating to events during illness course were obtained from the lifetime clinical & OPCRIT interviews.
Data to evaluate the course were obtained from a baseline questionnaire administered to all first and second year students during mandatory medical school lectures or after scheduled examinations prior to the commencement of the course.
The names of students in each class who pursued an additional research opportunity within 1 yr following the conclusion of the course were obtained through a survey sent to all students 1 yr out from their in-class research experience.
The courses were named as follows: Integrated Biology and Statistics, Integrated Biology and Calculus, and Integrated Biology and Discrete Math, and a separate rubric (IBMS) for the courses was obtained.
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