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Time was included as a factor with four levels – one for each assessment - to account for possible nonlinearities in the course of scale scores.
However, we did not include items on medications since neither patients nor experts did address the topic during the course of scale development.
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There are costs to be saved, of course, economies of scale much explored by US newspaper chains, such as Gannett, which like one set of reporters doing the same story for print, broadcast and internet, because time and journalists cost money.
In the course of larger scale studies degenerate oligonucleotides or sets of oligonucleotides representing proviral sequence variants should be employed.
In the course of the scale-up of the DOTS-Plus program, the management of drug-susceptible and drug-resistant TB was integrated for the continuation phase.
We, therefore, believe that the insights gained from this study are representative of the health system strengthening and support needs experienced by the TB services in Karakalpakstan in the course of the scale-up of ambulatory-based management of TB.
The importance of glycogen (metabolism) for growth and fitness of C. glutamicum might be observed in the course of large-scale industrial cultivations, when abiotic parameters repeatedly change.
Most known FTVs have been identified during the course of large-scale genome/exome screening studies (involving either patient panels or apparently healthy individuals from the general population).
In seminal recommendations, the American College of Medical Genetics and Genomics (ACMG) endorsed 56 medically actionable genes that clinical laboratories should generally analyze and report in the course of genome-scale sequencing.
In this case our principal interest was in the relative orientation of the two domains, and the variation of this orientation in the course of large-scale flexible motion.
Temperature and pH can be determined in shake flasks fermentations [ 13, 14], but agitation and oxygenation of the culture should be specifically studied in the course of the scale-up process [ 15– 17].
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