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The resulting time course of node activities is shown in Fig. 5b-c.
a Time course of node activity (based on 10,000 simulations) in response to PI3K inhibition from time = 2.
c Time course of node activity in response to PI3K inhibition at time = 2 in cells with constitutive PDK1 and SGK1 activity.
The resulting time course of node activities is shown in Fig. 4, where time is scaled so that the time unit is equal to the average time needed to update a slow node.
b Time course of node activity in response to PI3K inhibition at time = 2 in cells with full activity of PIM (top) or reduced PIM activity (10% chance of inactive PIM at any time step) (bottom).
C-erbB-2 expression is of no value to predict the clinical course of node negative patients in the current practice.
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b-d Time courses of node activity (average node state) in response to Growth Factor (GF) in the presence of RTKi, a RAS activating mutation, and MEKi.
b-c Time course of selected nodes, each representative of a different pathway.
Few reports have focused on the course of swollen nodes after resection of a primary cancer.
Of course, there are other effects that cause the line of nodes to turn, and that's been a major stumbling block in the attempt to detect frame dragging.
For patients who come to surgery after a course of neoadjuvant therapy, node status at that time remains a highly significant indicator of prognosis, whether this is after neoadjuvant chemotherapy or after neoadjuvant endocrine therapy.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com