Sentence examples for course of malignancy from inspiring English sources

In contrast, due to numerous molecular alterations arising during the course of malignancy, a tumour is characterized by an abnormal response to its environment, which allows cancer cells to evade the normal mechanisms controlling cellular proliferation.

In contrast, due to numerous molecular alterations that arise during the course of malignancy, a tumour is characterized by an abnormal response to its environment, which allows cancer cells to evade the normal mechanisms that control cellular proliferation.

By the end of 2009 the National Patient Registry reported 32 children with the ICD-10 diagnosis 'E83.3 Disorders of phosphate metabolism and phosphatases', but four of these patients had hypophosphatasia, and five had transient hypophosphatemia in the course of malignancy, premature birth, or other underlying condition.

The role of MR imaging for the depiction of bone marrow infiltration by hematologic malignancies is controversial and depends on the type, stage and clinical course of the malignancy.

Oncological emergencies can occur at any time during the course of a malignancy and can be the initial manifestation in some patients [2].

Despite admission in the ICU of patients with hematologic malignancies seems not to affect long term prognosis, early readmission seems to have a pejorative impact on the course of the malignancy.

The relative roles played by intrinsic and microenvironmental factors may vary over the course of the malignancy process.

Therefore it is important to establish whether modulation of the upstream or downstream targets of the PKC, either inhibition or restoration of activity, would be sufficient to change the course of the malignancy.

Biomarkers are tumor and host characteristics that either define the natural course of a malignancy irrespective of therapy (prognostic) or the probability of patient benefit from a therapy administered (predictive) [ 2].

In addition, there was a considerable increase in the risk of death from NMSC, suggesting these skin cancers may be more aggressive in CLL patients given the typically benign course of these malignancies.

This new variant seems to have a benign course with no evidence of malignancy or extracutaneous involvement.