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Llamas were immunised with various types of antigens and the antibody responses were examined during the course of immunisation.
MenC conjugate vaccine failure strains were recovered from 33 patients in the UK who had completed a course of immunisation yet contracted meningococcal disease [11].
However, there are a few reports of MenC disease developing in subjects who have completed a course of immunisation [11], [12], and these could be caused by strains with increased resistance to complement-mediated killing due to insertion of IS1301 in the sia/ctr IGR.
5 It also explains the tendency for children not to complete the whole course of immunisation.
This is a technique where antibodies made against a first course of immunisation, (i.e. those to the immunodominant epitopes), are then given passively to inhibit the antibody response to these epitopes when a second course of immunisation is given.
Similar(55)
Most data on childhood persistence of anti-HBs and the incidence of 'breakthrough' HBV infections following an accelerated course of HBV immunisation are from high-prevalence countries, 6 where boosting of anti-HBs titres through natural exposure 7 may be more frequent.
It involves a course of three immunisations for those over 15 (two for under 15) and protects against the strains of HPV that cause most cervical, anal, and genital cancers, including some mouth and throat cancers.
16 A performance based financing system, launched in 2005, rewards community health worker cooperatives, health centres, and district hospitals for better patient follow-up and improved primary care indicators, such as the proportion of women delivering at health facilities and children receiving a full course of basic immunisations.
The clinical course of infection following immunisation and challenge was followed by monitoring rectal temperature and lymph node enlargement and microscopic examination of smears prepared from needle aspirates of the lymph node draining the site of infection for the presence parasitised cells.
A child was defined as overdue if, according to the PCT record, they had not received a complete course of primary infant immunisations by 6 months, first dose MMR and PCV/Hib-MenC boosters (ie, 12 13 month immunisations) by 16 months or second dose MMR and dTaP-IPV (ie, pre-school booster, given at 3 years 4 months (40 months)) by 44 months.
53 Another study in 1800 healthy infants showed that when administered together with routine vaccines, a primary immunisation course of 4CMenB is immunogenic against three reference strains expressing one of three vaccine antigens.
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