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Coleman, R. E. & Rubens, R. D. The clinical course of bone metastases from breast cancer.
To determine the effect of intravenous zoledronic acid 5 mg on the extent and course of bone loss after spinal cord injury (SCI).
Having identified the three parameters, we used the model to predict the course of bone formation in two previously published in vivo studies.
Although, there are a lot of factors that influence fracture healing, experimental studies have shown that the interfragmentary movement (IFM) is one of the main regulators for the course of bone healing.
Because the time course of bone loss or bone gain distribution was not uniform in the metaphyses of the tibia, we subdivided the PTM into three zones (medial, central, and lateral) to observe the different bone loss or bone gain patterns after ovariectomy and/or raised cages.
The purpose of this study was to establish the normal time course of bone loss in the OVX rat model, and to determine the ability to detect morphological changes in vivo compared to cross-sectional study designs where animals are sacrificed at each time point.
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A whole steamed flounder looked just as spectacular, but it proved an obstacle course of bones.
Thus, we were not able to analyse the time-course of bone changes.
Bone may release its lead content into the bloodstream in the course of normal bone metabolism and may release lead at increased rates during active bone demineralization in later life (Gerhardsson et al. 1993; Hernandez-Avila et al. 2000; Rosen 1983; Silbergeld et al. 1988; Symanski and Hertz-Picciotto 1995).
5– 8 The clinical course of metastatic bone disease is relatively long and characterized by sequential skeletal complications, including bone pain, fractures, hypercalcemia, and spinal cord compression.
The patients with bone metastasis were classified according to the bone metastatic burden, and they were also separately classified into groups according to the course of the bone metastasis.
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