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In conclusion, children under 3 years old, chronic malnutrition at ART initiation, chronic diarrhea after the start of ART, drug substitution during the course of ART, and having CD4 count less than 50 at base line were independent predictors of increased risk of treatment failure.
The pooled estimates of health utilities and trends throughout the course of ART provided in this study provide valuable information about the effect of ART on HIV/AIDS patients health related quality of life, which in turn can support developing economic models for evaluating the cost-effectiveness of HIV/AIDS treatment strategies.
Future research needs to further elucidate the determinants of ART knowledge, in order to ensure that education and counseling of ART patients is effective and appropriate at different stages in the course of ART.
One consideration to reduce this obstacle is more flexible ART dispensation (>30 days) to reduce the burden of clinic visits earlier in the course of ART.
It is an image which literally changed the course of art history".
Each piece intervenes in the normal course of art and society, creating a turbulence.
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"Warburg was without doubt the most original thinker on art-history of our time, and entirely changed the course of art-historical studies," Clark wrote.
They changed the course of modern art history.
The whimsical, lyrical abstractions of Klee also had great influence on the course of modern art.
If Gerstl had continued in this vein, he might have changed the course of European art.
It was he who led his family on the journey that changed the course of modern art.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com