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Their assumption of constant substitution rates was reflected in the exponential time course of amelioration toward the equilibrium proportion.
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The identical time course of symptom amelioration after early improvement in patients treated with antidepressants of all classes or with placebo strongly suggests a common biological mechanism, which is not specific for a particular antidepressant medication.
Multiple studies reported an association between the time course of symptom amelioration of MDD and the performance in word fluency, cognitive flexibility and working memory tasks [ 31, 38, 39, 42- 45].
The virtually identical time course of symptom amelioration after early improvement in patients treated with antidepressants of all classes or with placebo strongly suggests that early improvement and the successive time course of response reflect a common biological mechanism, which is not specific for a particular antidepressant medication.
These experiments argue against the interpretation of the inferior olive as the sole source of OPT, but they do not offer an alternative mechanism that can explain many of the features of OPT, including its frequency of ∼2 Hz, the variability of its waveform in different patients, its slow time course of development and its amelioration or disappearance after many years.
In rats injured on postnatal days 6 or 30 (P6 or P30, respectively) and injected with FK-506 after the injury, signs of amelioration in the course of epilepsy were observed.
Of course due to amelioration processes the species proposed could be different from the donor species.
In epileptic rats injected with FK-506 or CsA, signs of significant amelioration of the course of epilepsy accompanied by longer survival periods were observed.
This time course of expression also reflects the progression and amelioration of the phenotype (see Fig 3A).
Another method of amelioration would be a more extensive use of the crematorium.
General feeling is that he came to Berlin in search of amelioration.
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