Our findings coupled with the documented role of Cath B in other CNS pathologies make this potent protease an attractive candidate for involvement in the tissue destruction associated with the secondary injury cascade following SCI.
This, coupled with the documented association between the Wnt co-receptor Lrp6 mutant eye phenotype and an RA signaling deficit (Zhou et al., 2008) prompted us to address the possibility that the RA signaling response was downstream of surface ectoderm Wnt ligands.
Coupled with these work placements, several lab courses ….
Physical coverage is again tightly coupled with these limits.
On the other hand, Akt presents credible candidature in light of its established role in S6K regulation coupled with its documented inhibition by bupivacaine [ 11, 26].
Through bioinformatic analyses of genes potentially regulated by the differentially expressed microRNAs, coupled with a documented gene expression profile [ 33], we identified putative biological functions and pathways, including insulin-like growth factor signaling, through which these microRNAs may affect the bleomycin-induced lung response.
The similarities of this model with the human disease, coupled with documented frequent XBP-1s overexpression in human MM, serve to implicate XBP-1s dysregulation in MM pathogenesis.
The Story Algebra, or more generally the process algebra approach provides a formal framework that promises a formal describing method for modeling precisely the event triggered processes coupled with data in document format within an Enterprise Architecture Framework.
To be reliable these macroevolutionary studies must consider groups possessing a high quality fossil record coupled with a well documented history of past environmental changes encompassing geological, ecological, climatic and biogeographical events [ 1].
The strikingly higher HIV prevalence for younger women compared to younger men in sub-Saharan Africa [41], [42], coupled with a growing literature documenting women's increasing participation in migration in the region [12], [28], [31], [37], [43], raises the question of how much of this disparity may be attributable, in part, to a differential risk of HIV with migration for males and females.
A complete characterization of Blochmannia in these genera is beyond the scope of the current study, but ideally will include additional representatives of each genus to test for symbiont persistence and stability, and will be coupled with ultrastructural work to document the location of bacteria within host tissues or cells.
