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Compared with our previously reported strategy, which was applied to TRN inference in the yeast cell cycle [25], this new scheme includes an integrative use of PPI and PDI data (hereafter called molecular interaction data) from thirteen publically available databases coupled with the detection of significant network motifs for each transcription factor.
This discovery, coupled with the detection of an extensive suite of predicted conjugation-related genes, provides additional evidence that A. ferrooxidans was capable of undergoing conjugation.
This observation coupled with the detection of ShSSA in homogenates of S. haematobium adult worm, eggs, miracidia, cercariae and schistosomula by microplate ELISA and USDA, indicated that ShSSA may be distributed in all the life-cycle stages of the parasite.
This, coupled with the detection of auto-antibodies for the ubiquitination factor E4A, specifically in enteroendocrine cells during Crohn's [ 11], has brought some focus upon the possible role of enteroendocrine cells in the pathogenesis of inflammatory bowel disease (IBD).
Coupled with the detection of unmodified lysine 128, this suggested that K126 of chicken H2A (equivalent to K127 in Xenopus and human) might be the predominant residue for BRCA1/BARD1-dependent ubiquitin conjugation in vitro.
Development of murine mAbs for robust and extensive screening of FFPE samples coupled with the detection of anti-tumour activity in novel indications provide rationale for expanding the application of SGN-75 for the treatment of multiple CD70 expressing cancers.
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The increased frequency of human infection with H7 viruses in recent years, coupled with the continued detection of H7 influenza viruses in poultry in both Europe and North America, suggests that future human infections with viruses within this subtype are likely to occur.
At the time, a DEA official explained that using drones to deliver drugs was "a new trend in smuggling". "This method will only allow a small amount of drugs to be flown at a time," the official said, "and, coupled with the ease of detection, does not make this method very profitable to these drug trafficking organizations". Not to mention: It crashed.
The process of determining the optimal L is coupled with the one of signal detection, and this leads to the following structured GLRT (SG) detector: Λ SG ′ X = max 1 ≤ l ≤ K Λ SG, l ( X ) = max 1 ≤ l ≤ K max μ 0, Σ 0 f X ; μ 0, Σ 0 max μ 1, l, Σ 1, l f X ; μ 1, l, Σ 1, l ≷ ℋ 1 ℋ 0 γ.
The adoption of articular cartilage calcification as a surrogate marker of OA disease, coupled with the development of improved detection methods for BCP crystals, could enable trials of targeted anti-crystal therapies with biological endpoints and a fast turnaround time.
These findings, coupled, with lack of detection of BiP in BALF (Figure 3A), suggested that this ER protein accumulates in the LB but is not secreted, perhaps because of its association with the inner surface of the limiting membrane.
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