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The most difficult cases involve a loose prosthesis coupled with deficient metaphyseal bone stock rendering a basic revision procedure impossible.
This coupled with deficient insulin secretion suggestive of deteriorating β-cell function underlies the development of GDM [17].
In developing countries, due to rapid industrialization, excessive application of metals and synthetic chemicals in the terrestrial environment coupled with deficient environmental management have led to a large-scale pollution in the environment.
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The members felt that "the accident was not the result of a chance malfunction in a statistical sense, but rather resulted from an unusual combination of mistakes, coupled with a somewhat deficient and unforgiving design".
Furthermore, expression of retrotransposons was elevated in Miwi2- and Mili-deficient testis, coupled with a loss of DNA methylation at these loci [21], [23].
26 These findings, coupled with our observations in A4gnt-deficient mice, suggest that αGlcNAc loss is associated with tumorigenesis of differentiated-type but not undifferentiated-type adenocarcinoma.
These data coupled with the aforementioned human ISG15-deficient patient susceptibility to BCG infection highlight the in vivo relevance of ISG15 as an antibacterial factor (Bogunovic et al., 2012).
Conversely, a deficient MMR system coupled with high MGMT expression levels may mediate TMZ resistance.
One model-predicted cause of this profile is deficient priming signals coupled with enhanced growth factor bioavailability.
Unlike in subjects who are clinically normal at the time of testing, in a patient with AHA the pitfall in the laboratory diagnosis of G6PD deficiency is that, as a result of the selective destruction of the older, more deficient red cells coupled with the entry in circulation of numerous reticulocytes, there will be a transient substantial increase in G6PD activity.
PON2-deficient mice display elevated hepatic oxidative stress, coupled with an exacerbated inflammatory response, because of PON2-deficient macrophages.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com