As mentioned above, in NER deficient cells, the lack of lesion removal coupled to the failure to activate the G1 DNA damage checkpoint in response to UV irradiation allows a large amount of DNA lesions to go into S phase.
Mr. Mandela said an absence of political solutions to a long-running ethnic conflict coupled with a failure to reorganize the armed forces and integrate rebel soldiers together sustained a situation in which "the population of Burundi has become hostage to violence from all sides in the conflict".
Its lack of disabled staff, coupled with a failure to involve service users in decision-making and to help them live more independently, has led to run-ins with disability rights activists who accuse the charity of institutionalising disabled people in crumbling mansions.
Those defeats, coupled with a failure to reach the knock-out stages of the World Cup, have seen Scotland slip to 12th in the world rankings behind Argentina, Tonga, Samoa and Italy.
Decades of tough-on-crime laws coupled with a failure to finance prison programs have left prisoners stacked three bunks high in prison gymnasiums and hallways throughout the state.
The lack of jobs, coupled with a failure to transform failing schools in areas that serve mainly black and mixed-race children, has limited social mobility for many South African children, the report said.
However, the unreliability of Japan's economic statistics, coupled with a failure to adjust for the extra day of the leap year, mean that the figures may overstate the real strength of Japan's recovery.See article: Japan's rising bankruptciesRetail sales in America fell by 0.3% in May, following a decline of 0.6% in April.
Coupled with a failure to maintain album track order in some downloads, that puts the Sansa off my playlist.
But Rifi said it is exactly this type of rhetoric, coupled with a failure to adequately combat the rise of Islamophobia that could fuel extremism among disengaged and alienated youth, rather than curtail it.
"One thing I eventually came to realize in the Army," I observed in my new book, "is that it's not material shortfalls that get you into trouble most but, rather, a lack of situational awareness and understanding coupled with a failure to understand the future implications of decisions and actions made today".
