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In case of multiple sub-steps, the collective transition might be considered as a group of coupled steps rather than a single transition state in the classical sense.
If H-abstraction is not the fully rate-limiting of the two coupled steps, there is scope for the intrinsic KIEs to be even larger than those reported.
3′ End processing involves two tightly coupled steps, cleavage and polyadenylation, and requires a polyadenylation signal (PAS) and a downstream sequence element (DSE) [ 3].
Additional proton coupled steps also kinetically constrain energy transduction including the slow diffusion rates of plastoquinone [ 37] as well as the relatively slow turnover (100 200s-1) of the ATP synthase complex [ 41, 42].
Similar(56)
The microstrip resonator was designed using coupled stepped impedance open stubs.
Fmoc-protected amino acids were coupled step-by-step on the solid phase.
Oxidation of NADPH by oxidized glutathione was then recorded photometrically in a coupled step (λ=340 nm).
By coupling steps together, unfavorable equilibria can be driven towards completion.
Open image in new window Fig. 2 Loose coupling step between reservoir and network models.
The synthesis involves coupling step to obtain the precursor followed by radiofluorination.
It was hypothesised that the ZnO was active for the dehydrogenation and the ZrO2 the aldol coupling step.
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