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In this review, we will highlight some of the platforms that have been developed for the enrichment of glycopeptides from complex samples, and introduce emerging combination platforms that couple the sensitivity and accuracy of MS to the exquisite selectivity of nano-platforms.
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The above is a reflection of the fact that HPV prevalence of and concordance among couples is not only highly variable but also depends on the sexual behavior of the couples, the sensitivity of the tests employed, and more importantly on the differences between acquisition rates among men and women.
The proposed hybrid sensor aims to couple the high sensitivity of the well known Kretchmann prism excitation design with the more robust integrated waveguide design.
When coupled with the sensitivity of inverter-based generation to transient frequencies, the provision of ancillary services from other sources than generators becomes increasingly important.
This paper assesses the role of hillslope/channel coupling for the sensitivity of upland geomorphic systems, using evidence from a 30-year monitoring programme of geomorphic change in the Carlingill valley, Howgill Fells, northwest England.
Powerful separation techniques coupled with the sensitivity and selectivity of mass spectrometry, are used to identify these proteins.
Comparing graphs of response amplitude vs flash strength before and during perfusion with MFA in the same cone highlights how junctional coupling transforms the sensitivity profile of the cone making it responsive to dim flashes, thereby widening its dynamic range.
Purification of glycoproteins by affinity chromatography on GalMBP requires minimal sample preparation prior to affinity chromatography and the high yields, coupled with the sensitivity of mass spectrometry, allowed characterization of both protein and glycan components without requiring radiolabeling or immunoprecipitation.
The vagaries of agricultural production coupled with the sensitivity of malaria therapeutics to cost of goods considerations led Jay Keasling and co-workers to apply synthetic biology principles to artemisinin production.
The well-defined profile of epigenetic modifications associated with Th lineage commitment, coupled with the sensitivity of the early developmental period, has led to speculation that factors that disrupt these pathways may increase the risk of allergic disease (Vuillermin et al. 2009).
By coupling the high sensitivity and specificity of MS with highly quantitative and reproducible nature of NMR spectroscopy, it is possible to perform more comprehensive metabolic profiling than allowed by each analytical method alone.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com