Exact(1)
The large size of the candidate regions and the high number of genes described within them, led us to couple linkage analysis with high-throughput sequencing-based mutational screening as a new strategy for variation detection.
Similar(59)
Our data indicate a highly dynamic and tightly coupled linkage between AD inputs, runoff chemistry and river water chemistry.
However, as the reaction proceeds, the solution acidity increases and the initially formed phenazine-like segments function as the nucleate for the free aniline monomers to polymerize through para-coupling linkage.
This increase of B is accompanied by an increase of coupling linkage disequilibrium (LD) between selective sites (r > 0) that also becomes relevant for h = 0, implying the presence of coupling groups of recessive deleterious alleles.
No lines were observed to be resistant against one pathogen and susceptible to the other, indicating that if Lr20 and Sr15 are two genes (not a single pleiotropic gene), they are in complete coupling linkage in the Excalibur/Kukri population.
In the intraspecific map, the number of crossovers across all chromosomes of an individual varied from 44 to 97, with an average of 67.5, ignoring two individuals with an abnormally high number of crossovers on a couple of linkage groups.
To cope with the nonlinearities of coupled mechanical linkage dynamics of articulated systems and the inherently strong nonlinearities of hydraulic actuator dynamics, the proposed controller is designed based on the recently introduced Virtual Decomposition Control (VDC) approach.
Identification of specific allele variants contributing to improved resistance may be useful to breeders by allowing selection of resistance alleles in coupling phase linkage with favorable agronomic characteristics.
A promising approach to identify disease genes is the candidate gene approach coupled with linkage analysis using microsatellites from the candidate gene region.
A prime example of how founder population characteristics coupled with linkage to medical records can accelerate discovery was recently produced by studying the Finnish population [ 10].
Tightly-linked QTL can be optimal for breeding if the desirable resistance alleles are in coupling phase linkage and there is no detrimental linkage drag associated with the chromosomal region.
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