One issue with current studies is that regulations only count reported work hours, even though many residents may be working more than 80 hours off the books.
The median counts reported for 'pathological responders' might therefore be falsely high, thus resulting in a loss of significance.
This was borne out by mass spectrometry proteomics [ 39] and query of the PeptideAtlas database [ 40] that showed very low AGR2 signature peptide counts reported to date.
Quantitative abundance estimates were derived from the peptide counts reported for each prey, and an experimentally derived connectivity matrix M was obtained after normalization (see Methods).
Another study virtue is the high kappa coefficient value of the IEL counts reported by the two independent investigators, reassuring the reliability of our results.
At the time, the FDA told BuzzFeed News it was still counting reports from 2017.
We analyzed the data by counting reports that matched a given pair of drugs and the AE specified in a putative association, disregarding the reporting source.
It also counts reports that date back to previous generations.
They counted reports of tick sightings in each of the 3110 continental U.S. counties to determine whether those counties hosted an established population or just a few individuals.
Similarly, investigators used product coding based on medical record review for specific mechanisms, which could have been misclassified leading to under- or over-counting reporting.
