We speculate that TCER-1, just like its mammalian counterpart, functions as part of the general transcription-coupled export machinery, whereas PUF-8, through its ability to bind specific mRNAs and to interact with proteins involved in mRNA export, such as NCBP-2, provides an alternative export pathway for some of the mRNAs.
We chose four human cDNAs (h LIG1, h SSRP1, h PPP1CA, and h PPP1CC) for which their yeast gene counterparts function in chromosome stability and assayed in yeast 35 tumor-specific missense mutations for growth defects and sensitivity to DNA-damaging agents.
In vitro studies suggested the ocular fluid and relevant levels of soluble GAGs could compete for VEGF-A with its surface counterpart that function as co-receptors for VEGFR2 or by directly interfering with ligand-receptor interactions.
Although, these connectors are similar to their electrical counterparts in function and outward appearance, they are actually high precision devices that have to centre the small fiber so that its light gathering core lies directly over and in line with the light source.
If the nuclear receptors are modified by the lipid moiety, then it is entirely possible that the membrane receptors are the same as their nuclear counterparts and function to regulate synaptic excitability.
9- 11 However, genetic data have suggested that mammalian HtrA2, like its bacterial counterpart, normally functions as a stress response gene, preserving mitochondrial integrity.
Discrete optimization is notoriously more difficult than its continuous counterpart because functions are generally not convex and because a modification of only one of the variables can significantly change the likelihood of the model.
Ling et al. demonstrated that miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of epidermal growth factor receptor 3. In prostate cancer, Pasqualini et al. showed that miR-22 and miR-29a were less abundant in the cancerous tissue compared with the benign counterpart and functioned as tumor suppressors by modulating cancer associated targets LAMC1 and Mcl-1.
It is important to point out that an I-function and its T-function counterpart are basically in complementary distribution.
Unlike the non-conditional PCRLB, its conditional counterpart is a function of the past history of observations and is a more accurate representation of the system׳s performance.
