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In hMLH1−/− and hMSH6−/− cells containing TGFBR2 OF or ACVR2 OF sequences, newly fluorescent cells were observed ranging between 0.14% and 1.22% (median 0.32%) net fluorescence over counterpart cell lines containing MR TGFBR2 OF or MR ACVR2 OF sequences.
Although, it is unclear in these models what the putative ligand in the counterpart cell might be, CD98 binding to galectins has been reported in other cell types [48].
Notch signaling is triggered by the binding of Notch ligand to the Notch receptor in the counterpart cell.
However, the effect of the ectopic expression of Bax in the progressive counterpart cell line Pro was not investigated in this work [ 36].
The mouse embryonic normal hepatic cell line (BNL CL2) and its SV40 large T-antigen-transformed counterpart cell line (BNL SV A.8) were also purchased from ATCC.
BL41/B95.8 is the counterpart cell line infected in vitro with EBV strain B95.8 and was kindly provided by Martin Allday (Ludwig Institute for Cancer Research, London, UK).
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Analysis of the RNA-Seq data showed a high degree of correlation between the triplicates and a significant differentiation between the UCB HSCs transduced with shRNAs against NAP1L3, compared to their control counterpart cells (Fig. 6a).
CaSki cells exhibited a lower whole-cell stiffness and a softer nuclei zone compared to the normal counterpart cells.
CBP expression was higher in PS-deficient MEFs than in the normal counterpart cells (Figure 6A).
All proteins from HIV-infected cells were compared with those expressed in the uninfected counterpart cells at different time points.
This extracellular membrane bound peptidase was not detected in any of the numerous uninfected counterpart cells tested (Figure 2).
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