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In fact, a visual inspection of the KEGG apoptosis pathway clearly shows the up-regulation of caspase 3 (CaSP3), a known inducer of cell death, and the under-expression of BCL2 and BIRC3 (IAP gene in the KEGG map), which counteract this action.
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In this context, approaches to counteract the action of survivin in tumour cells have been proposed with the dual aims of inhibiting tumour growth through promotion of spontaneous apoptosis and of enhancing the tumour cell response to apoptosis-inducing agents (Altieri, 2003b).
However, this mitotic activity is only transient and does not fully counteract the action of J1ICD.
d Cancer cells, through the overexpression of anti-apoptotic proteins or inactivation of pro-apoptotic proteins, counteract the action of BAX/BAK and evade MOMP formation.
Thus the enhanced P-Akt expression resulting from FOXO3a induction in MCF-7 is insufficient to counteract the action of activated FOXO3a, resulting in an overall decrease in cell viability.
Hence it is possible that the variation in dnaN in C. difficile could be the result of a recombination-mediated mechanism to counteract the action of antibiotic like ciprofloxacin.
Yeast and fungi are able to develop resistance to counteract the action of azoles.
Consequently, resident cells of the CNS should be able to counteract the action of potential auto-reactive lymphocytes.
PcG complexes maintain Hox gene silencing whereas TrxG complexes counteract the action of PcG complexes (reviewed in [ 4]).
Accordingly, hop resistance is a multifactorial property that requires different mechanisms to counteract the action of iso-alpha acids.
Echinacea, an immunostimulant, can counteract the action of the immunosuppressants (e.g., the corticosteroids prednisone, methotrexate, and cyclosporine) used to treat immune disorders[ 17, 18].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com