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The Anastrepha DsxF and DsxM proteins are able to counteract the function of Drosophila DsxM and DsxF respectively, just as these latter proteins behave towards one another.
However, this immune regulation can counteract the function of CD4+ or CD8+ effector T cells and paradoxically dampen the control of infection.
A likely explanation for the inability of transfected TFs to generate myelin-expressing cells was the possible existence of a repressive histone code that would counteract the function of activating TFs.
Hepcidin is reported to counteract the function of ferroportin, a major cellular iron exporter protein in the membrane of macrophages and the basolateral site of enterocytes, by inducing its internalization and degradation [2].
Some microbial pathogens possess effectors that counteract the function of components in the PTI signalling cascade.
Both Smc3 acetylation and Scc1 acetylation appeared to counteract the function of Wapl to establish cohesion.
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Two discrete AZINs are expressed in mammalian cells, AZIN1 and AZIN2, both of which counteract the functions of AZ thereby activating ODC and depressing its degradation as well as enhancing polyamine uptake [14] [18].
Finally, the Anastrepha DsxF and DsxM proteins were found to counteract the functions of Drosophila DsxM and DsxF respectively, reflecting the normal behaviour of the latter proteins towards one another.
The PTEN phosphatase serves at the molecular level to counteract the functions of phosphoinositide 3-kinase, which promotes proliferation and cell survival, in part through activation of mTOR (Sansal & Sellers 2004).
JNK1 counteracts the function of WOX1 in apoptosis [13], [15].
More efficient splicing of IgMPTB was observed with ΔNΔRS than with SF2/ASF (Figure 4, lanes 14 and 15), suggesting that the RS domain of SF2/ASF is not required for counteracting the function of the PTB site I silencing element.
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