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To counteract the development of cancer, these organisms developed a number of cell extrinsic and intrinsic tumor-suppressing mechanisms one of which is cellular senescence, a proliferative arrest that forces cells to exit the cell division cycle permanently.
A major challenge to counteract the development of resistance to antibiotic treatment is to get a better understanding of how bacteria react to antibiotics.
The ability of 4-oxo-4-HPR to act through at least two unrelated mechanisms could probably allow to counteract the development of drug resistance.
To counteract the development of resistance in Lepidopteran field populations, it would be beneficial to have additional resistance technologies with varying modes of action available.
This distinctive mode of action could allow 4-oxo-4-HPR to efficiently target tumor and eventually to counteract the development of drug resistance.
This indicates that hepatic and muscular defects in the oxidative phosphorylation may counteract the development of diabetes, despite its deleterious effects on β-cell survival.
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Consequently, the idea of tolerance implies the necessity, for the dissenting group or individuals, to become illegitimate if and when the established legitimacy prevents and counteracts the development of dissent.
The combination, at doses ineffective individually, even counteracted the development of lung oedema induced by sephadex in the rat.
Furthermore, this increased oxygen supply might be beneficial as it counteracts the development of an anaerobic metabolism after trauma-haemorrhage, thereby preserving energy-rich phosphate (e.g. ATP) levels and attenuating a tissue energy depth.
Ablation or suppression of critical genes controlling hepatic lipogenesis [8] [11] counteracts the development of hepatic steatosis in animals receiving high-fat diets.
In ovine OA-induced lung injury, rhAPC dampens the increase in pulmonary artery pressure and counteracts the development of lung edema and the derangement of arterial oxygenation.
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