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They may confer additional robustness to the pluripotent state to counter differentiation stimuli (Ying et al., 2003a).
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The female dorsal modifications impair the attachment ability of male suction cups, but each antagonistic novelty in females corresponds to counter-differentiation of suction cups in males.
This finding increases our understanding of CSC function in tumor heterogeneity and the importance of identifying drugs to counter de-differentiation rather than targeting CSCs.
Figure 2(a) shows that the counter output after differentiation (i.e., the number ) is 2, for three reference clock periods out of four, and it is 3 for one clock period out of four.
This effect, called gas multiplication, makes the output electric pulse proportional to the ionization produced by the radiation entering the counter and thus permits differentiation among particles of various kinds and energies.
Overexpression of Nanog has been reported to counter the induction of differentiation as a result of LIF removal (Chambers et al., 2003).
Also, the differentiation represents "counter-programming," he writes, with ABC tending to humanize the news, and CBS emphasizing hard news.
In brief, hybridomas were generated using standard techniques, tested for specificity to myostatin and counter screened for growth and differentiation factor-11, transforming growth factor-β1, activin A and BMP-5 binding.
Nevertheless, multiple colonization and recent isolation can counter forces leading to genetic differentiation between islands and monophyly [ 20].
In addition, USP10 is identified as a TBP-specific deubiquitinase and counters TBP degradation and myocyte differentiation.
We next examined whether expression of genes involved in differentiation were activated to counter-balance the decreased expression of those associated with replication.
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