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While such approaches are certainly suited to identify inhibitors that react with an enzyme, their activity in vivo could well be disappointing if they are not absorbed to penetrate internal cell membranes to arrive at their molecular target(s).
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And it could well be a doubly disappointing day if Nicholls, with no future in the National Hockey League to look forward to, also has to look back at a past with no glory.
They could well be.
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This could well be true.
It could well be sense8tional.
This could well be boilerplate.
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Ford Motor could well be one.
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