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The phrase 'could significantly increase' is correct and usable in written English.
You can use it when referring to a potential change in something or the possibility of something increasing in size, amount, or intensity. For example, "The implementation of a new regulation could significantly increase employee morale."
Exact(60)
This device could significantly increase their quality of life.
That could significantly increase the pressure on companies operating there.
The prepared wavelike interface could significantly increase the joining area.
The rebels also began discussing forming a coalition, a move that could significantly increase their power.
Analysts say the deal could significantly increase Yahoo's fortunes in China.
It is not clear, however, that the Fed could significantly increase interest rates.
Such parallel litigations are inefficient and could significantly increase legal costs.
The results showed that HBV could significantly increase Lsd1 mRNA and protein levels (Fig. 3a, b).
What's more, the fact that we will accept competitors' cups means we could significantly increase that figure".
In fact, I think there are two where we could significantly increase our security with a negligible cost in freedom.
Work is still progressing on hundreds, if not thousands, of DNA samples, which could significantly increase these totals.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com