This new concept could not only overcome the a/m problems, but should also create different topography on the workpiece surface which is appropriate for some functional applications.
PEGylated PAMAM-mediated delivery could not only overcome the limitations of dendrimer such as drug leakage, immunogenicity, hemolytic toxicity, systemic cytotoxicity but they also have the ability to enhance the solubilization of hydrophobic drugs and facilitates the potential for DNA transfection, siRNA delivery and tumor targeting.
The computational results on PPI dataset have shown that the algorithm could not only overcome the drawbacks of sensitivity to clustering center, but also have the highest accuracy and recall rate, the lowest P value, and the best f-measure among the competing algorithms.
The Democrats could try to force through organization changes without Republican support, but they would almost certainly face the threat of a Republican filibuster, which could only be overcome by a vote of 60 senators.
Although both Mr. Barak and Mr. Sharon insisted today that they were still hoping to join forces, they expressed what seemed to be irreconcilable views about peacemaking -- differences that could only be overcome, some experts predicted, by a wave of terrorism that forced them into an emergency coalition.
Some former officials and political consultants said that the Republican voter registration gap could only be overcome under extraordinary circumstances — a citywide focus on crime before Mayor Giuliani was elected in 1993, or the Sept. 11 attacks weeks before Mayor Bloomberg's initial victory.
Slumped on their knees, the Hibernian players could only feel overcome by a familiar regret.
This lower efficacy could only be overcome by increasing the dose, which in turn could result in an increased risk of side effects.
The Prussian War Ministry was interested, but some initial skepticism could only be overcome through a series of successful demonstrations.
(p. 36) (The only good I can see coming out of Prop 140 was the unseating of former Assembly Speaker Willie Brown whose entrenchment seemed that it could only be overcome via term limits.
