The results were striking: Raf-1-deficient epidermis was completely refractory to tumour formation in both models; in addition, using the genetic model we could show that Raf-1 ablation enforces complete, rapid regression of established lesions that never recur, although Ras activation persists throughout the life of the animals.
This unsettling situation need never recur.
One hopes this will never recur.
Her breast cancer never recurred.
The scale of the disaster also led to efforts to ensure it never recurred.
It however, almost never recurs if the primary lesion is in muscle - 0% [ 8].
He developed cancer of the bladder relatively early in life, and could never be sure it would not recur; eventually, he contracted cancer of the oesophagus.
According to the theater's general director, Michel Franck, Michèle Losier, the mezzo-soprano who portrays the protagonist in Marc-Antoine Charpentier's "Médée" from 1793, has complained of recurring nightmares and said she could never portray Medea if she had children.
Something that came through on Father's Day, when we invited people to write about their fathers' tools on the Web site, was this recurring theme of fathers who could never be what they wanted to be, a generation of men who lost out, who had to do what was expected of them".
It reads, "May such injustice and suffering never recur".
