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In the present study the patients are significantly older than the healthy subjects, which could have increased a difference in results.
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Although the prevalence of MDR-TB was low (1.4% rifampicin resistant), poor outcome in these patients could have increased the difference in DALYs between the two model arms by up to 10% if patients were to be treated with effective drugs.
Even if the difference in the antihypertensive medication profile between the two groups (more RAAS inhibitors in the control group and more alpha-blockers in the dialysis group), could have increased the magnitude of the difference in vascular aging [ 26, 27], the potential source of bias should have been blunted by the adjustment for systolic blood pressure applied to MogPWV.
The slight increase in proportion of fourth year students in the intervention group could have increased the total score resulting in no difference in total scores between both groups.
The characteristics of individuals who chose not to participate in the client survey may have differed from those who responded, and while unlikely, these differences could have increased or decreased the probability that survey fields contained erroneous information, biasing file audit results.
A Hawthorne effect could have increased the nurses' compliance during the short study period, thus decreasing the difference between the manual and automated periods.
It cannot be excluded that this could have increased the mean values of florbetapir uptake in favour of showing a significant difference in relation to the HC subjects.
Some differences have increased over time.
We could not measure a significant difference in D2 activity levels although they seemed to have increased in prolonged critically ill animals.
We all could have made a difference.
If they had done, it could have made a difference".
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CEO of Professional Science Editing for Scientists @ prosciediting.com