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Woman, she argued, "had chained herself to her place in society and the family through the maternal functions of her nature, and only chains thus strong could have bound her to her lot as a brood animal".
Therefore, although the RGD ligand theoretically could have bound to any of the three integrin conformations, the measured mean specific FR would not necessarily reflect a shift in the conformational equilibrium.
Moreover, first RNA species could have bound exogenous molecules carrying reactive groups, such as adenine, using them as catalytic cofactors [ 20, 21].
Interestingly, considering a metal-catalysed origin of metabolism gives rise to an attractive hypothesis about how the first enzymes could have formed: simple RNA or (poly)peptide molecules could have bound the metal ions, and thus increased their solubility, concentration and accessibility.
To further exclude the possibility that the "HGF" that had been secreted before serum starvation could have bound the c-Met receptor and triggered constitutive c-Met phosphorylation, PC-3 cells were quickly rinsed with a wash buffer to strip any potential pre-existing "HGF" molecules on the cell surface [ 29].
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DARPin could be reaching the tissue in its free form and binding resident cells there and/or we could be detecting cells that have bound DARPin in the periphery and migrated to the lymph node.
In the longer term, the results could loosen the knots that have bound unions with the dominant Democratic Party and its mayors and supervisors, which would be a striking change for a city where labor leaders like Harry Bridges once held sway.
Since CD146 is found in a soluble form in human plasma (Bardin et al, 2003) these CD146-positive events could result from platelet aggregates which have bound soluble CD146 resulting in specific staining of these complexes with the anti-CD146 antibody.
I would have bound my breasts if I could have.
As you have bound them to hell -- they bind you to hell".
Stick what you have bound.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com