The induction of increased procoagulant activity could be speculated to be caused by platelets activated by absorbed intestinal endotoxin [ 22], as increased intestinal permeability has been demonstrated in sled dogs [ 21, 23] or by the proinflammatory state documented by the increased CRP after the 68 km sled pull.
Concerning the increasing nestin positive area for NRX and its correlation to the IL-2 receptor expression in the late phase of inflammation it could be speculated that this might cause a bigger stimulus for the body and could result in a more pronounced inflammatory reaction.
It could be speculated that S.s bacteriocin could cause the organelle damage of Candida thallus and then affect the synthesis and expression of protein and DNA in Candida, finally resulting in transfer interruption of material, energy, and information, and the cell turned to death.
It could be speculated that it may be caused by development of antibodies against adalimumab in some of the patients [ 17].
Given the similar appearance of polyQ-intoxicated pica yeasts, a related cause for these phenotypes could be speculated on, in particular as pica responds to the growth on non-fermentative carbon sources likewise with a general inability to form any colonies [ 40].
It could be speculated that the impairment of local pulmonary defences caused by the persistent irritation of tobacco smoke may play a role.
It could be speculated whether the high frequency of voids was caused by either insufficient preparation of the root canals or insufficient filling of the root canal or, perhaps more likely, a combination of both.
It could be speculated, therefore, that repeated distance running, but not walking, caused some damage that would make it harder to recover from the damaging exercise bout.
It could be speculated that S100B as well as homocysteine are related to effects on e.g. hippocampal areas that cause unspecific symptoms that occur in different psychiatric disorders.
However, considering that avian influenza causes an excessive immune response, it could be speculated that appropriately regulated immunity does not hamper the body's normal resistance to AIV.
