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As other ministries and government offices are identified as needing outside expertise, India could be asked to increase these numbers and administrative programs could be specifically targeted to receive specialized training.
Previously, we demonstrated for the first time that fetal DNA in maternal plasma could be specifically targeted by epigenetic (DNA methylation) signatures in the placenta.
With respect to S-phase events both mouse models and studies on cancer-derived cells revealed that accumulation of cyclin D1/CDK4 complexes triggers DNA re-replication [36] and, thus, could be specifically targeted in cancer cells.
We therefore asked if this interaction could be specifically targeted to interfere with tumour dissemination.
These profiles, although still preliminary, may help in identifying "pathways of therapy failure" that eventually could be specifically targeted.
As pAKT plays an important role in cell survival, these results suggest that hypoxic cells could be specifically targeted by pAKT-inhibition.
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Initiatives promoting outings and visits by family and friends could also be specifically targeted.
Microbubbles could also be specifically targeted to inflamed endothelium with antibodies to P-selectin (CD62P).
The report should stimulate the development of blockers of the GC-C and CFTR intestinal secretory pathways, and this will have potential for wide application to life-threatening infectious diarrheas, in addition to the chronic, mild, non-fatal diarrhea afflicting this family; these diarrheas could then be specifically targeted with personalized or precision medicine.
Could the immune response be specifically targeted to aid patient recovery?
However, subgroups that would be specifically targeted in lifestyle intervention studies (such as the definitely obese) could be relatively small.
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