From the results, we found that several DEGs with higher degrees in module 1 could be regulated by IRF8, for example, CTSS, CCL5, and PLEK.
Therefore, the rate of melanosis could be regulated by pre-cooking for an appropriate time.
miR-200 family could be regulated by some signaling pathways, for example, abnormal expression of AKT1 and AKT2 causes dysregulation of miR-200 family to regulate epithelial-mesenchymal transition (EMT) and CSCs self-renewal (Iliopoulos et al., 2009).
As an example, a number of downstream targets could be regulated by a master gene, for example a transcription factor.
We thus hypothesized that morphine potentiated SIV-mediated neuronal apoptosis likely via downregulation of the tropic factor PDGF-B chain in neurons, and this in turn, could be regulated by microRNA(s) specific for PDGF-B.
Tightly regulated expression and interaction of a multitude of genes for ovarian folliculogenesis could be regulated by these miRNAs.
After successful implantation of these myoblasts into damaged mouse muscles, luciferase expression in the matured progeny cells could be regulated by oral application of doxycycline for at least 1 month.
Therefore, we searched for miRNAs that could be regulated by Bmi1 in CPCs, as plausible modulators of stem cell function.
For example, the trafficking, within-membrane localization, membrane retention, and gating of many multipass membrane channels is influenced by palmitoylation (Shipston, 2011), and we have identified a wide range of palmitoylated P. falciparum membrane channels here (PfCRT, for example), which could be regulated in a similar manner.
Similarly, EMMPRIN expression could be regulated by the S100A4 receptor RAGE (receptor for advanced glycation end products) (Bao et al, 2010) and the NF- κB signalling pathway (Hagemann et al, 2005), which is also activated by S100A4 (Boye et al, 2008).
An antibody array was used to screen for candidate cytokines that could be regulated by hypoxia.
