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To decrease the differences between prior definitions of bleeding, this complicated evaluation is most likely necessary, but its complexity and the associated inconvenience for users could be limitations to its wide application in clinical practice.
Another limitation for the assay is that the medical relevance of the assay could be limited.
Although the process has been shown to demineralize shrimp shells with very low mineral residue, the use of a large chemical ratio and high temperature due to a lack of optimization could be major limitations for its industrial application.
The risk of bias was evaluated by one author and this could be a limitation for this process, although this limitation could be counteracted considering that PEDro scale is a broadly validated tool.
Such inter-session variability could be a limitation for its use in certain conditions, especially for those requiring longitudinal evaluation of disease progression and/or response to treatment.
That could be a limitation for companies with existing investments in hardware and software.
It can be argued that this scoring system could be a limitation for our conclusions.
This inconsistency could be a limitation for an international comparison of individual diseases.
This could be a limitation for the control of RA with chemokine inhibitors.
This could be due to some limitations for gene flow between Camden Park and other populations.
However, given the relative low uptake of the tracer and the spatial resolution of clinical SPECT (6.7 15.3 mm) [22], the fact that 99mTc-maraciclatide is a SPECT tracer could be perceived as a limitation for its widespread use in human arterial inflammation imaging, especially for coronary artery imaging.
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