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Thus, we could hypothesize that the secretion-defective mutant proteins are either incorrectly folded or have altered electrostatic surfaces, which could affects LGI1 export.
Since the differences occur when the cells restart their cellular division, m8 protein could affects the cell viability as well as the division capacity.
In order to investigate epithelial atrophy, six fields of epithelial layer without obvious neutrophils influx, which could affects the epithelial integrity, were randomly selected and the thickness of the epithelium was analysed by a Carl Zeiss Axio Vision 2.05 image processing and analysis system (Zeiss).
It is also known that dacryocystitis is common in middle and elderly age and more commonly in women but of course could affects all age groups [ 16].
It can be argued that stigma may affect government efforts at curtailing the spread of HIV/AIDS [ 9, 16, 46- 49] since it could affects patient's attendance at health centres for obtaining ARV and regular medical check-ups or adherence of patients to treatment plans [ 13- 15, 48].
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